Cell Line Origin
Human Caucasian lung, large cell carcinoma, drug resistant
Cell Line Description
COR-L23/5010 has been derived from the parent line, COR-L23 (Sigma Catalogue number. 92031919) by continuous exposure to increasing concentrations of doxorubicin (also known as adriamycin). The cells overexpress multidrug resistance-associated protein (MRP) and express a 190kDa membrane-protein connected to the degree of drug-resistance. COR-L23/5010 have a higher resistance than COR-L23/R (Sigma Catalogue number. 96042339).
Application
MRP studies, drug-resistance studies
DNA Profile
STR-PCR Data: Amelogenin: X
CSF1PO: 11
D13S317: 10,11
D16S539: 11,13
D5S818: 10,12
D7S820: 9
THO1: 9
TPOX: 8,11
vWA: 19
Culture Medium
RPMI 1640 + 2mM Glutamine + 1.0μg/ml doxorubicin + 10% FBS
Subculture Routine
Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37°C It is recommended to culture the cells without drug after resuscitation until the first passage.
Other Notes
Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.
biological source: human lung. growth mode: Aggregates in suspension. karyotype: Not specified. morphology: Not specified. products: Not specified. receptors: Not specified. technique(s): cell culture | mammalian: suitable. relevant disease(s): cancer. shipped in: dry ice. storage temp.: −. 196°C.Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51162630
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 96042338-1VL
- Temperature Control Device:
- Yes
