Mirosamicin

RASSF7 is a RAS association domain-containing protein that is needed for spindle formation during mitosis in neural tubes . RASSF7 also enhaces cell survival by blocking the MKK7/JNK signaling pathway .

Cell Line Description Ma-Mel-19 (ESTDAB-152) was established from the cutaneous/subcutaneous metastasis in a 62 year-old female patient with metastatic melanoma (superficial spreading melanoma stage IV). The Ma-Mel-19 cell line is one of more than

Cell Line Description Ma-Mel-27 (ESTDAB-168) was established from the cutaneous/subcutaneous metastasis in a 58 year-old female patient with metastatic acrolentiginous melanoma (stage IV). The Ma-Mel-27 cell line is one of more than 170

Cell Line Description Ma-Mel-6 (ESTDAB-150) was established from the lymph node metastasis in a 58 year-old male patient with metastatic melanoma (nodular melanoma stage IV). The Ma-Mel-6 cell line is one of more than 170 characterized melanoma

Cell Line Description Ma-Mel-7 (ESTDAB-137) was established from the lymph node metastasis in a 68 year-old male patient with metastatic melanoma (nodular melanoma stage IV). The Ma-Mel-7 cell line is one of more than 170 characterized melanoma

A cell-permeable pyrimidinone compound that inhibits the exonuclease activity of Mre11, component of the MRN (Mre11-Rad50-Nbs1) complex, and prevents MRN-mediated activation of dimeric ATM (IC 50 = 12 &#181M) in cell-free p53 Ser15 phosphorylation