Novobiocin calcium

A cell-permeable compound that acts as a selective, potent, and reversible inhibitor of non-muscle myosin II. Inhibits the ATPase and gliding motility of human platelets (&#8804100 &#181M) without affecting myosin light chain kinase (MLCK)

Anticancer, antiviral agent that is especially effective against leukemias. Induces apoptosis in human myeloid leukemia cells and in rat sympathetic neurons.

A less toxic, potent, synthetic derivative of the ansamycin benzoquinone antibiotic Geldanamycin Streptomyces hygroscopicus (Cat. No.

A cell-permeable, irreversible inactivator (~3 mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme. Disrupts the blood-brain barrier and causes severe energy (ATP)

4-Hydroxynonenal, CAS 75899-68-2, is a major aldehyde product formed by peroxidation of &#969-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation. A major aldehyde product formed by peroxidation of

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-&#945-D-glucosaminidase. Can be used to test for Sanfilippo B syndrome.

Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity. Useful as a reference standard in enzyme assays.

Synthetic, therefore free of any contamination with related natural products. Warning Toxicity: Harmful (C) Reconstitution Following reconstitution, aliquot and freeze (-20&#176C).

Synthetic, therefore free of any contamination with related natural products. Warning Toxicity: Harmful (C) Reconstitution Following reconstitution, aliquot and freeze (-20&#176C).

Synthetic, therefore free of any contamination with related natural products. Warning Toxicity: Harmful (C) Reconstitution Following reconstitution, aliquot and freeze (-20&#176C).

A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (K i = 4 nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (K i = 0.087, 4.

A cell permeable, reversible, and substrate competitive phosphatidylinositol ether analog that potently and selectively inhibits Akt (PKB) (IC 50 of 5.0 &#181M).