Calusterone

A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III, IC 50 = 300 nM). Has positive chronotropic, ionotropic, and vasodilatory effects on the heart.

A cell-permeable methyl ester derivative of Pepstatin A (Cat. No.

A cell-permeable, pyrrolidine small molecule that promotes single human embryonic stem cell survival up to 20-fold over background (EC 50 = 3.9 M), with equal or higher potency than Y-27632 (Cat.

Analysis Note Assay (GC, area%): &#8805 99.0 % (a/a) Melting range (lower value): &#8805 108 &#176C Melting range (upper value): &#8804 112 &#176C Identity (IR): passes test

A relatively non-toxic hydroxamic acid-containing histone deacetylase (HDAC) inhibitor. Facilitates transcriptional activation (TGF&#946/Smad4) in both stable and transient reporter assays in a concentration-dependent manner.

A cell-permeable steroidal compound that selectively inhibits SHIP1&#8242 polyphosphatase activity toward PI(3,4,5)P3 (IC 50 = 10 &#181M), but not SHIP2 5&#8242 or PTEN&#8242 polyphosphatase activity toward PI(3,4,5)P3 (IC 50 &gt1 mM).

A cell-permeable sialylic acid analog that upon cellular uptake is transformed into a CMP-Neu5Ac (a href=http://www.emdmillipore."

Packaging This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service .