Parnaparin

Application Fluorescent detector of nitric oxide in culture medium, tissue sections and biopsy cells. Analysis Note Final solution contains approx.

Amino Acid Sequence Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys [Disulfide Bridges: 1−29, 3−18, 8−28] General description Chemical structure: peptide Biochem/physiol

A water-soluble phenanthridinone derivative that acts as a potent anti-inflammatory agent and a reversible inhibitor of poly(ADP-ribose) polymerase (PARP EC 50 = 20 nM). Shown to be about 10,000-fold more potent than the prototypical PARP

A potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP IC 50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.

A cell-permeable, adenosine-substituted, isoindolinone compound that acts as a potent inhibitor of PARP-1 (IC 50 = 45 nM). Shown to offer cytoprotective effects against oxidative damage in cells and in in vivo models of reperfusion injury and

A potent inhibitor poly(ADP-ribose) polymerase (PARP IC 50 = 0.40 &#181M).

A cell-permeable, water-soluble phenanthridinone-derivative that acts as a potent inhibitor of poly(ADP-ribose) polymerase (PARP EC 50 = 20 nM). Shown to be about 10,000 times more potent than the prototypical PARP inhibitor, 3-Aminobenzamide (Cat.

A cell-permeable, water-soluble phenanthridinone-derivative that acts as a potent inhibitor of poly(ADP-ribose) polymerase (PARP EC 50 = 20 nM). Shown to be about 10,000 times more potent than the prototypical PARP inhibitor, 3-Aminobenzamide (Cat.

A cell-permeable isoquinolinedione compound that potently inhibits PARP-1 activity (pIC 50 = 7.35 IC 50 = 45 nM) in a NAD + -competitive and reversible manner, while affecting PPAR-2 activity with a 100-fold lower potency.