Calcitonin

A potent, cell-permeable, and irreversible inhibitor of calpain. Biochem/physiol Actions Cell permeable: yes Primary Target calpain Product does not compete with ATP.

A cell-permeable dipeptidyl &#945-ketoamide that acts as a potent, highly selective, reversible, and active site inhibitor of calpain-1 and -2 (K i = 140 nM and 41 nM, respectively). Weakly inhibits cathepsin B (K i = 6.

Synonym(s): Z-Leu-^a-aminobutyric acid-CONH(CH2)3-morpholine, Z-L-Abu-CONH(CH2)3-morpholine Formula: C26H40N4O6 Formula weight: 504.60 CAS Number: 145731-49-3 Harmonized Tariff Code:  2924.19

Synonym(s): Z-L-Nva-CONH-CH2-2-Py Formula: C26H34N4O5 Formula weight: 482.60 Harmonized Tariff Code:  2924.19

A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC 50 = 20 nM for purified rabbit calpain II). Does not inhibit either papain or trypsin.

A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide (Cat. No.

Calpeptin (Z-Leu-nLeu-H) is a cell permeable, peptide aldehyde inhibitor. It is more sensitive to calpain I compared to other inhibitors, such as Z-Leu-Met-H and leupeptin.

Calpeptin (Z-Leu-nLeu-H) is a cell permeable, peptide aldehyde inhibitor. It is more sensitive to calpain I compared to other inhibitors, such as Z-Leu-Met-H and leupeptin.

Biochem/physiol Actions Highly specific inhibitor of protein kinase C (IC 50 = 50 nM) requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.

Biochem/physiol Actions Highly specific inhibitor of protein kinase C (IC 50 = 50 nM) requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.

Biochem/physiol Actions Inhibits tubulin polymerisation (IC 50 =24 &#956M), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest. Packaging Bottomless glass bottle.

Digitonin, a steroidal saponin extracted from the purple foxglove plant (Digitalis purpurea), stands as a versatile non-ionic detergent crucial for cell biology and biochemical research. Its unique attributes position it as a valuable asset in the