Immunomodulating drugs

Keratin, type I cytoskeletal 20 (UniProt P35900 also known as CK-20, Cytokeratin-20, K20, Keratin-20, Protein IT) is encoded by the KRT20 gene (Gene ID 54474) in human. Cytokeratin-20 (Keratin-20 or K20) belongs to a family of highly conserved

LAT (Linker for activation of T cells) is a transmembrane adaptor protein that plays an essential role in T cell receptor (TCR) signal transduction pathways. LAT is phosphorylated on multiple tyrosine residues upon TCR engagement, recruits several

The mammalian target of rapamycin (mTOR), also known as FRAP, RAFT, or RAPT, is a ubiquitously expressed serine/threonine kinase that belongs to the phosphoinositide 3-kinase&#8211related kinase (PIKK) family. mTOR functions as a downstream

The mammalian target of rapamycin (mTOR), also known as FRAP, RAFT, or RAPT, is a ubiquitously expressed serine/threonine kinase that belongs to the phosphoinositide 3-kinase&#8211related kinase (PIKK) family. mTOR functions as a downstream

NUMA1 or NUMA protein is an interesting and major component of the nuclear matrix of eukaryotic cells. NUMA1 is a highly abundant protein component that appears to serve a non-structural role but is needed for mitotic spindle poles and centrosome

Pseudopodium-enriched atypical kinase 1 (Peak1 KIAA2002, or sgk269) is a ubiquitous non-receptor tyrosine kinase that belongs to the NFK3 family. It interacts with actin filaments via its N-terminal actin-targeting region.

This antibody recognizes a variety of proteins that are phosphorylated during mitosis. Progression of cells from interphase to mitosis involves alterations in cell structures and activities.

Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmits TGF-&#946 signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the

The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a

High affinity nerve growth factor receptor (EC 2.7.

BDNF/NT-3 growth factors receptor (EC 2.7.

Ubiqutin (Ub) is initially produced as a 229-a.a.