Immunosupressant antibodies

TIE2/TEK (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin-like loops separated by

Ubiquitin-specific-processing protease 7 (USP7) is also known as Ubiquitin carboxyl-terminal hydrolase 7 or Herpesvirus-associated ubiquitin-specific protease (HAUSP). USP7 is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves

Specificity Alpha Synuclein, phospho Serine 129. The antibody recognizes a protein of ~15 kDa corresponding to alpha synuclein, phospho Serine 129 in lysates from rat cortex.

Amyloid precursor proteins (APPs) are transmembrane glycoproteins that are found in a wide range of tissues. APPs have 3 main isoforms, namely, APP695, APP751 and APP770 that are derived from alternative splicing events in cells.

Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators.

MET, a gene for receptor tyrosine kinase, was first isolated in human osteosarcoma-derived cell line. Hepatocyte growth factor (HGF) has been identified as the natural ligand for the c-Met receptor protein.

Specificity CPI-17 phosphorylated on Threonine 38. Immunogen Peptide corresponding to amino acids 35-46 of human CPI-17.

Receptor tyrosine-protein kinase erbB-4, also known as, Proto-oncogene-like protein c-ErbB-4 (4ICD or E4ICD), and encoded by the gene names Erbb4 or Tyro-2, plays an essential role as cell surface receptor for neuregulins. ERBB4 regulates

There are two kinds of IGF receptors based on their relative affinities for IGF-1 versus IGF-2. The IGF-1 receptor (IGF-1R) prefers IGF-1 over IGF-2 and weakly binds insulin.

Specificity Integrin B1 phosphorylated on Thr788/789 Immunogen C-terminal Peptide Application Research Category Cell Structure Research Sub Category Integrins This Anti-phospho-Integrin &#9461 (Thr788/789) Antibody is validated for use in WB for

Specificity Integrin B1 phosphorylated on Tyr783 Immunogen C-terminal Peptide Application Anti-phospho-Integrin &#9461 (Tyr783) Antibody detects level of phospho-Integrin &#9461 (Tyr783) &amp has been published &amp validated for use in WB.

Specificity Integrin B1 phosphorylated on Tyr795 Application Anti-phospho-Integrin &#9461 (Tyr795) Antibody is an antibody against phospho-Integrin &#9461 (Tyr795) for use in WB. Quality Routinely evaluated by immunoblot.