Immunosupressant antibodies

The gene ITGB3 (integrin subunit &#946 3) encodes the &#946 subunit of integrins, which are transmembrane &#945/&#946 heterodimers. There are 18 &#945 subunits and 8 &#946 subunits identified in mammals that associate with each other to form

ITCH is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. ITCH regulates the transcriptional activity of

Keratin, type I cytoskeletal 18 (UniProt P05783 also known as Cell proliferation-inducing gene 46 protein, CK-18, Cytokeratin-18, K18, Keratin-18) is encoded by the KRT18 (also known as CYK18, PIG46) gene (Gene ID 3875) in human. Cytokeratin-18

LAT (Linker for activation of T cells) is a transmembrane adaptor protein that plays an essential role in T cell receptor (TCR) signal transduction pathways. LAT is phosphorylated on multiple tyrosine residues upon TCR engagement, recruits several

The mammalian target of rapamycin (mTOR), also known as FRAP, RAFT, or RAPT, is a ubiquitously expressed serine/threonine kinase that belongs to the phosphoinositide 3-kinase&#8211related kinase (PIKK) family. mTOR functions as a downstream

Pseudopodium-enriched atypical kinase 1 (Peak1 KIAA2002, or sgk269) is a ubiquitous non-receptor tyrosine kinase that belongs to the NFK3 family. It interacts with actin filaments via its N-terminal actin-targeting region.

This antibody recognizes a variety of proteins that are phosphorylated during mitosis. Progression of cells from interphase to mitosis involves alterations in cell structures and activities.

Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmits TGF-&#946 signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the

The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a

High affinity nerve growth factor receptor (EC 2.7.

Immunogen phosphatase, orphan 2 recombinant protein epitope signature tag (PrEST) Application All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by

Immunogen phosphatase, orphan 2 Application All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the