Radiopharmaceuticals and contrast media

Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS [1,2,3,4] .

Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS [1,2,3,4] .

Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS [1,2,3,4] .

Structure confirmed. Purity = 98%. Will ship with Certificate of Analysis (CoA)

Fmoc-Cys(tBu)-OH

The side-chain tBu group is stable to TFA and iodine oxidation. Treatment with MeSiCl 3 /PhSOPh removes t -Bu and cyclizes in one step without scrambling existing disulphide bonds.

Building block for introduction of cysteinyl residues by Fmoc SPPS. The t-Buthio group can be selectively removed using thiols [1] or tributylphosphine [2,3] .

Structure confirmed. Purity = 98%. Will ship with Certificate of Analysis (CoA)

Structure confirmed. Purity = 98%. Will ship with Certificate of Analysis (CoA)

Fmoc-Cys(Thp)-OH is a new building block for Fmoc SPPS, in which the sulfhydryl group is protected with the acid-cleavable tetrahydropyranyl (Thp) group [1] . The use of Fmoc-Cys(Thp)-OH has been shown to give superior results to the corresponding

Fmoc-Cys(Trt) Wang resin

Pre-loaded resin for synthesis of peptide acids containing a C-terminal cysteine amino-acid residue by Fmoc SPPS. The base NovaSyn TG is a composite of low cross-linked polystyrene and 3000-4000 M.