Cilostamide

Biochem/physiol Actions PDE3 catalyzes the phosphodiester bond hydrolysis, observed in secondory messengers such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Inhibitors of PDE3 are generally inotropic and

A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III IC 50 = 70 nM). Biochem/physiol Actions Cell permeable: yes Primary Target PDE 3 Product does not compete with ATP.