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DS-1001b (DS 1001) (C007B-137229)

Catalog No.
C007B-137229
Mfr. No.
D414241-100mg
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $643.26
List Price: $714.73

InformationDS-1001b (DS 1001) DS-1001b is an oral selective inhibitor of mutant IDH1 R132X with potential antineoplastic activity and is designed to penetrate the blood-brain barrier.TargetsIDH1 R132XIn vitroDS-1001b impairs the proliferation of

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InformationDS-1001b (DS 1001) DS-1001b is an oral selective inhibitor of mutant IDH1 R132X with potential antineoplastic activity and is designed to penetrate the blood-brain barrier.TargetsIDH1 R132XIn vitroDS-1001b impairs the proliferation of IDH1 mutant chondrosarcoma cell lines and decreases 2-HG levels.In vivoContinuous administration of DS-1001b impairs tumor growth in xenograft mice.Cell Research(from reference)Cell lines:JJ012,L835 cell lines Concentrations:0-10µM Incubation Time:72 h. Specification: 0.98 Molecular Formula: C29H29Cl3FN3O4 Molecular Weight: 608.92 PubChem CID: 139600317 Isomeric SMILES: CC1=CN(C2=CC=CC(=C12)/C=C/C(=O)O)C(=O)C3=C(ON=C3C4=C(C=C(C=C4Cl)Cl)Cl)C(C)(C)F.CC(C)(C)N
UPC:
51112007
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
D414241-100mg
CAS:
1898207-64-1
Product Size:
100mg

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