Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation ( IC 50 of 260.7 nM) and shape change ( IC 50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammationIn VitroElubrixin has an inhibitory effect on neutrophils in a dose-dependent fashion. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CXCR2|IL-8. Specification: 0.99 Molecular Formula: C24H25Cl2FN4O7S2 Molecular Weight: 635.51 EC Number: 629-901-2 PubChem CID: 23634419 Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
- UPC:
- 51111653
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E649974-10mg
- CAS:
- 960495-43-6
- Product Size:
- 10mg
