Rabbit anti Human Estrogen Receptor beta Antibody, Polyclonal, could be used for WB, IHC and so on.ApplicationWB: 1/500-1/1000IHC: 1/50-1/100Protein FunctionNuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. Specification: ExactAb™, Validated, 0.6 mg/mL
- UPC:
- 51182045
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab102374-1ml
- Product Size:
- 1ml
