Application
Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid has been used:
- in Dulbecco′s phosphate-buffered saline (DPBS) to induce the weakening of cell-to-cell junctions
- as an extracellular calcium chelator to study the role of calcium in axonal mitochondria degeneration
- as a component in lysis buffer for lysing mouse mucosal cells for western blot analysis
A chelating agent useful for the determination of calcium in the presence of magnesium.
Biochem/physiol Actions
Ethylene glycol tetraacetic acid (EGTA) can chelate calcium (Ca2+) at a ratio of 1:1. It serves as an anti-coagulant when dissolved at 1 g per 100 ml of blood. EGTA can prevent the vesicular release in the nanodomain of single Ca2+ channels. This metal chelator can inhibit the activity of pseudolysin.
Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid A is a chelating agent used for the determination of calcium in the presence of magnesium.
- UPC:
- 51282528
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E3889-10G
