EUK-134 (C005B-313016)

Catalog No.: C005B-313016
Mfr. No.: SML0743-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $178.83

List Price: $198.70

Application EUK-134 has been used as an antioxidant. EUK-134 has been used to determine the mechanism underlying hypoxia-inducible factor-1α: (HIF-1α:) stabilization in human aortic endothelial cells (HAECs).

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Description
Specifications

Application

EUK-134 has been used as an antioxidant.

EUK-134 has been used to determine the mechanism underlying hypoxia-inducible factor-1α (HIF-1α) stabilization in human aortic endothelial cells (HAECs).

Biochem/physiol Actions

EUK-134 is a manganese-salen derivative that exhibit potent antioxidant activities. EUK-134 is a superoxide dismutase (SOD) that inhibits amyloid fibril formation, including islet amyloid polypeptide (IAPP), β-amyloid and lysozyme amyloid aggregation. It appears that EUK-134 disrupts the pre-formed amyloid fibrils. EUK-134 increases the viability of the SK-N-MC cells exposed to preformed IAPP fibrils.

Other Notes

air sensitive

UPC:: 12352200
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0743-10MG
CAS:: 81065-76-1

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