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exonuclease i, 10 u/mul

Exonuclease I, 10 U/muL

Catalog No.
C15-1427-195
Manufacturer No.
GEE70073X
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
PK
Price: $1,435.06
List Price: $1,594.51

Acts specifically on single-stranded DNA degrading it processively in the 3′- to 5′-direction, producing 5′-mononucleotides. Exonuclease I (Exo I) from  E.

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General description

Acts specifically on single-stranded DNA degrading it processively in the 3′- to 5′-direction, producing 5′-mononucleotides.

Exonuclease I (Exo I) from E. coli is an Mg2+ ion dependent exonuclease.

Application

Exonuclease I has been used to quantify the expression of 56 genes in each F2 XY gonad.

Biochem/physiol Actions

Exonuclease I (Exo I) from E. coli can degrade single-stranded DNA (ssDNA) from 3′ to 5′. It participates in various DNA repair systems, like, RecBCD-dependent homologous recombination, methyl-dependent mismatch repair and genomic tandem repeat maintenance.

Features and Benefits

  • Elimination of residual single-stranded DNA containing a 3′-terminus.
  • Measuring endonucleolytic cleavage of covalently closed circular (ccc) ssDNA.
  • Measuring DNA helicase activity.

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

UPC:
41105304
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
GEE70073X


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