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Factor IXa Activity Assay Kit (Fluorometric)

Catalog No.
C007B-169269
Mfr. No.
F486411-1kit
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $1,403.39
List Price: $1,559.32

DescriptionThe coagulation Factor IX (or Christmas factor) (EC 3.4.21.22) is a vitamin K-dependent serine protease. Factor IX is produced as an inactive precursor and is activated via cleavage by either factor XIa (contact pathway) or factor VIIa

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DescriptionThe coagulation Factor IX (or Christmas factor) (EC 3.4.21.22) is a vitamin K-dependent serine protease. Factor IX is produced as an inactive precursor and is activated via cleavage by either factor XIa (contact pathway) or factor VIIa (tissue factor pathway). In the presence of calcium ions and negatively charged membrane phospholipids, activated factor IX (FIXa) then binds to the activated Factor VIII (FVIIIa) and proteolytically activates factor X (FX) to factor Xa (FXa). Deficiency in factor IX causes hemophilia B, an X-linked bleeding disorder.Suitability: Suitable to determine the activity of purified Factor IX and to detect the activity of Factor IX in plasma and serum.Principle: This Factor IXa Activity Assay kit is based on the ability of FIXa to generate FXa. The generated FXa proteolytically cleaves a synthetic substrate and releases a fluorophore, AMC, which can be easily quantified by fluorescence microplate reader. The assay is simple, rapid, and can detect activity as low as 10 pg of FIXa in a variety of samples.}Preparation instructionsSuitable to determine the activity of purified Factor IX and to detect the activity of Factor IX in plasma and serum.PrincipleThis Factor IXa Activity Assay kit is based on the ability of FIXa to generate FXa. The generated FXa proteolytically cleaves a synthetic substrate and releases a fluorophore, AMC, which can be easily quantified by fluorescence microplate reader. Specification: sufficient for 100fluorometrictests Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/F486411-SCI_015d87a462586e6c70ae36bc59bf3c52.pdf
UPC:
41131708
Condition:
New
Availability:
8-12 weeks
Weight:
3.53 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
F486411-1kit
Product Size:
1kit

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