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FATOSTATIN HYDROBROMIDE (C005B-030096)

Catalog No.
C005B-030096
Mfr. No.
F8932-5MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
5
UOM
MG
Price: $241.72
List Price: $268.58

Fatostatin is a non-sterol diarylthiazole derivative. It prevents insulin-induced adipogenesis and lowers the amounts of fatty acid, triglyceride and low-density lipoprotein.

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General description

Fatostatin is a non-sterol diarylthiazole derivative. It prevents insulin-induced adipogenesis and lowers the amounts of fatty acid, triglyceride and low-density lipoprotein. Fatostatin has anti tumor and antimitotic properties.

Application

Fatostatin hydrobromide has been used:

  • to study its anti-cancer activity and effects on mitotic microtubule spindle
  • to study its effects on stomatal development
  • to prevent SREBP cleavage-activating protein (SCAP)-mediated escort of sterol regulatory element-binding proteins (SREBPs)

Biochem/physiol Actions

Fatostatin hydrobromide is an SREBP inhibitor. Fatostatin hydrobromide inhibits fat production and lowers glucose levels in mice by inhibiting SREBP (Sterol Regulatory Element Binding Proteins).

UPC:
51322703
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
F8932-5MG
CAS:
298197-04-3

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