FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone], 10 mg

FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone] is a potent uncoupler of oxidative phosphorylation in mitochondria. It is used as a positive control for mitochondrial membrane depolarization. FCCP disrupts the synthesis of ATP by trnasporting protons across mitochondrial inner membrane. It depolarizes the mitochondrial membrane potential. Features: Molecular weight: 254.17 Cas number: 370-86-5 Solubility: Soluble in DMSO (100 mM). Soluble in methanol, ethanol and acetone to20 mg/ml. Insoluble in water. Molecular Formula :C₁₀H₅F₃N₄O Stability : Stable at 4°C under desicating conditions for 1 year. Store at -20°C for long term storage. Store the dissolved FCCP in aliquotes at -20°C Recomended working concentration of FCCP for cells is 20 µM. It may vary depending on cell types and should be optimizedby user Applcation(s) FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone] is a potent uncoupler of oxidative phosphorylation in mitochondria. It is used as a positive control for mitochondrial membrane depolarization.