FERROSTATIN-1 (C005B-313195)

Catalog No.: C005B-313195
Mfr. No.: SML0583-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $192.20

List Price: $213.56

Application Ferrostatin-1 has been used to determine its inhibitory effect on the cell death profiles. Biochem/physiol Actions Ferrostatin-1 is a potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis.

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Description
Specifications

Application

Ferrostatin-1 has been used to determine its inhibitory effect on the cell death profiles.

Biochem/physiol Actions

Ferrostatin-1 is a potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis. Ferrostatin-1 prevents ferroptopic cell death in cancer cells and glutamate-induced toxicity in organotypic rat brain slices. It appears that Ferrostatin-1 controls lipid soluble ROS.

Ferrostatin-1 is an active radical-trapping antioxidant that traps peroxyl radicals, and thus serves as a potential inhibitor of ferroptosis. Ferroptosis is considered as regulated necrosis, which differs from apoptosis and autophagy. Ferrostatin-1 is known to show protective effects against HuntingtonÃ¢â‚¬Â²s disease and also prevents neurotoxicity induced by glutamate in cellular models.

UPC:: 51192443
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0583-5MG
CAS:: 347174-05-4

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