General description
Fibronectin is an extracellular matrix (ECM) glycoprotein. It is expressed in various cell types. Fibronectin exists as a dimer and is made up of identical subunits which are linked covalently via a disulfide bond at their C-termini.
Application
Fibronectin, Bovine Plasma has been used as an extracellular matrix (ECM) substrate to coat dishes or polyacrylamide hydrogels for adhering:
- human melanoma cancer cells
- human breast epithelial cells
- mouse embryonic fibroblasts
Biochem/physiol Actions
Fibronectin plays a role in cell adhesion, growth, migration, and differentiation. It binds to several molecules such as integrins, heparin, fibrin, and collagen.
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.3.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
single band by SDS-PAGE
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
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- UPC:
- 41116113
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 341631-1MG
- CAS:
- 86088-83-7
- Temperature Control Device:
- Yes
