FILIPIN COMPLEX FROM STREPTOMYCES FILIPINENSIS (C005B-008145)

Catalog No.: C005B-008145
Mfr. No.: F9765-25MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 25
UOM: MG

Price: $435.48

List Price: $483.87

Chemical structure: macrolide Application Filipin complex from Streptomyces filipinensis has been used as a profluorescence probe to detect the free cholesterol in cell. Biochem/physiol Actions Filipin is a polyene macrolide antibiotic and

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Description
Specifications

General description

Chemical structure: macrolide

Application

Filipin complex from Streptomyces filipinensis has been used as a profluorescence probe to detect the free cholesterol in cell.

Biochem/physiol Actions

Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action is unclear but may be due to altering membrane permeability. Filipin binds to model crystalline phase lipid bilayers containing cholesterol, and to liquid phase bilayers with or without cholesterol, in an orientation that forms membrane pores.It both inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.

Other Notes

Filipin contains 8 isomeric components, with filipin III as the major component.

UPC:: 51171623
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: F9765-25MG
CAS:: 11078-21-0

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