Flazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO - ) , with an IC 50 value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC 50 value of 71.99 μM for ONOO - . Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitorIn VitroFlazin significantly decreases cellular triglyceride (TG) by 12.0-22.4% compared with modeling groups and improved the TG and free fatty acid profile. Flazin efficiently reduces both cellular neutral lipid content by 17.4-53.9% and lipid droplets size by 10.0-35.3%. Flazin exhibits xanthine oxidase inhibitory with an IC 50 of 0.51 mM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:IC 50 : 85.31 μM (BSA), 0.51 mM (XOD),EC 50 : 71.99 μM (ONOO - ). Molecular Formula: C17H12N2O4 Molecular Weight: 308.29 PubChem CID: 5377686 Isomeric SMILES: C1=CC=C2C(=C1)C3=CC(=NC(=C3N2)C4=CC=C(O4)CO)C(=O)O
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- F648604-5mg
- CAS:
- 100041-05-2
- Product Size:
- 5mg
