General description
Fmoc-Pen(Trt)-OH is the standard building block for the introduction of penicillamine amino-acid residues by Fmoc SPPS. The side-chain thiol protecting group (Trt) is removed during the standard TFA-mediated cleavage reaction.
Associated Protocols and Technical Articles:
Cleavage and Deprotection Protocols for Fmoc SPPS
Application
Fmoc-Pen(Trt)-OH has been recently used in the synthesis of disulfide surrogate peptides.
Analysis Note
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51442712
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 8523390001