Force Biphenyl LC Column, 5um, 250 x 4.6mm

Ideal for bioanalytical testing applications like drug and metabolite analyses Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries Limits ionization suppression and allows simple, MS-friendly mobile phases Restek’s most popular LC stationary phase The culmination of 20+ years in LC, Force performance LC columns are long-lasting and reproducible, even under the stress of UHPLC. Premium quality is backed by the strength of our 100% Pure Satisfaction guarantee. And perhaps most important, Force columns are fully scalable between 3 or 5 μm HPLC and 1.8 μm UHPLC, so you can easily transfer and optimize methods without extensive calculations. The innovative Biphenyl is Restek's most popular LC stationary phase because it is particularly adept at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries. As a result, Biphenyl columns are extremely useful for bioanalytical testing applications like drug and metabolite analyses, especially those that require a mass spectrometer (MS). Increasing retention of early-eluting compounds can limit ionization suppression, and the heightened selectivity helps eliminate the need for complex mobile phases that are not well-suited for MS detection. Stationary Phase Category: Phenyl (L11) Ligand Type: Biphenyl Particle: 1.8 μm, 3 μm, or 5 μm fully porous silica Pore Size: 100 Å Carbon Load: 15% End-Cap: yes Surface Area: 300 m2/g pH Range: 2.0–8.0 Maximum Temperature: 80 °C Properties: Increased retention for dipolar, unsaturated, or conjugated solutes Enhanced selectivity when used with methanolic mobile phase Ideal for increasing sensitivity and selectivity in LC-MS analyses Switch to a Biphenyl when: Limited selectivity is observed on a C18 You need to increase retention of hydrophilic aromatics