General description
A chemically modified forskolin with greater stability and water solubility. Activates adenylate cyclase (EC50 = 13 µM).
Chemically-modified forskolin with greater stability and water solubility than the parent compound. Activates adenylate cyclase (EC50 = 13 µM). Inhibits 5HT-stimulated inositol phosphate accumulation in smooth muscle cells.
Biochem/physiol Actions
EC50 = 13 µM in activating adenylate cyclase
Primary Target
Adenylate cyclase
Warning
Toxicity: Harmful (C)
Reconstitution
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
Other Notes
Yang, C.M., et al. 1999. Cell Signal. 11, 697.
Hartzell, H.C., and Budnitz, D. 1992. Mol. Pharmacol.41, 880.
Chidiac, P., et al. 1991. J. Mol. Cell. Cardiol.23, 1255.
Laurenza, A., et al. 1987. Mol. Pharmacol.32, 133.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51131727
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 344273-1GM