GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a K i of 0.54 nM and a cell IC 50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2.In Vitro:GAK inhibitor 49 (compound 49) hydrochloride shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC 50 s of 28, 63 and >100μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Biological Activity:GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a K i of 0.54 nM and a cell IC 50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2. Specification: 10mM in DMSO Molecular Formula: C20H23ClN2O5 Molecular Weight: 406.86
- UPC:
- 12352208
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- G661712-1ml
- Product Size:
- 1ml
