General description
Recombinant human galectin-1 expressed in and purified from E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.
Recombinant, human galectin-1 expressed in E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.
Preparation Note
Further dilute into aqueous buffers as needed.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
Other Notes
Rabinovich, A., et al. 2002. Trends Immunol.23, 313.
Rabinovich, A., et al. 2002. J. Leukoc. Biol.71, 741.
Hughes, R.C., et al. 2001. Biochimie.83, 667.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Assay: ≥. 98% (SDS-PAGE). Quality Level: 100. form: solid. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze. solubility: water: 0.1-1 . mg/mL. shipped in: wet ice. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1.- UPC:
- 41106202
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 345831-50UG