General description
Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Reported to disrupt mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. Antibodies to GD3 can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. M.W. 1577.0 (based on tricosanoyl - 23:0).
Warning
Toxicity: Irritant (B)
Other Notes
DeMaria, R., et al. 1997. Science 277, 1652.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Molecular Weight: 1522.80. Empirical Formula: C70H123N3O30 · 2NH4. Quality Level: 100. Assay: ≥. 98% (TLC). form: solid. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze. color: white. solubility: water: 1 . mg/mL, chloroform/methanol (2:1): soluble. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51392606
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 345752-1MG