An antagonist of the transcription factor Gli, inhibiting Gli1 activation of gene expression with an IC50 value of 5 μM; does not affect signaling through several other pathways, supporting specificity for the Hedgehog pathway; has been shown to inhibit the proliferation of cancer cells, both in vitro and in mice.
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- UPC:
- 51181922
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 13841-5
- CAS:
- 500579-04-4
- Model Number:
- C830G47
- Temperature Control Device:
- Yes