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gb-110 hydrochloride (c09-1136-044)

GB-110 hydrochloride (C09-1136-044)

Aladdin

Catalog No.
C09-1136-044
Manufacturer No.
G659189-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $1,189.08
List Price: $1,321.20

GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca 2+ release in HT29 cells with an EC 50 of 0.28

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GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca 2+ release in HT29 cells with an EC 50 of 0.28 μM.Appearance:SolidIC50& Target:PAR2In Vitro:In an intracellular Ca 2+ (iCa 2+ ) mobilization assay using HT29 colon cancer cells, GB110 (EC 50 240±20 nM; pEC 50 6.7±0.05) is equipotent with the peptide agonist 2f-LIGRLO-NH2 (EC 50 210±30 nM; pEC 50 6.6±0.05), 10-fold more potent than SLIGRL-NH2, buBiological Activity:GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca 2+ release in HT29 cells with an EC 50 of 0.28 μM. Specification: 0.99 Molecular Formula: C33H49ClN6O5 Molecular Weight: 645.23
UPC:
12352107
Condition:
New
Availability:
8-12 weeks
Weight:
1.09 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
G659189-25mg
Product Size:
25mg


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