Application
GBR 12909 dihydrochloride has been used as a dopamine transporter (DAT) inhibitor:
- to study its effects on LPS-induced mRNA expression on the proinflammatory cytokines in the mouse striatum
- to study its effects on neurotransmitter release in zebrafish brain
- in DA uptake assay in mice striatal fraction
Biochem/physiol Actions
GBR 12909 may show pharmacotherapeutic effects against cocaine addiction.
GBR 12909 is a highly selective dopamine reuptake inhibitor with behavioral effects similar to cocaine.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
- UPC:
- 51291906
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D052-250MG