Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase ( GCase ) activator ( EC 50 =3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouseIn VitroGcase activator 2 has low metabolic clearance in human and mouse with CL values of 10 and 12 μL/min/mg, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:β-Glucocerebrosidase. Specification: 0.98 Molecular Formula: C21H24N4O2 Molecular Weight: 364.44
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- G647842-5mg
- CAS:
- 2759897-35-1
- Product Size:
- 5mg
