An immunosuppressive mycotoxin which inhibits 20S proteasomal chymotrypsin activity (IC50 = 10 μM), preventing activation of NF-κB; induces apoptosis in monocytes and dendritic cells and reduces phagocytosis by neutrophils; inhibits geranylgeranyltransferase I and farnesyltransferase (IC50 = 17 and 80 μM, respectively); potently suppresses viral infection by Nipah and Hendra virus in vitro (IC50 = 149 and 579 nM, respectively).
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- UPC:
- 51203202
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- 11433-1
- CAS:
- 67-99-2