GNE-9278 (C007B-357224)

Catalog No.: C007B-357224
Mfr. No.: G647283-10mg
Mfr. Name: Aladdin Scientific
Qty/UOM: 1
UOM: EA

Price: $306.46

List Price: $340.51

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Description
Specifications

GNE-9278 is a highly selective positive allosteric modulator of NMDAR that acts at the GluN1 transmembrane domain (TMD). GNE-9278 acts on activated NMDARs to increase peak current and agonist affinityIn VitroGNE-9278 (50 μM) slows deactivation with multiple agonists (D-Glu, L-Glu and L-CCG-IV) and enhances the potency of both Glu and Gly. GNE-9278 robustly potentiates GluN2A, 2B, 2C and 2D-containing NMDARs as measured by calcium influx assays from HEK cell lines with EC 50 s of 0.74, 3.07, 0.47, and 0.32 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:NMDAR. Specification: 0.99 Molecular Formula: C21H27N5O3S Molecular Weight: 429.54

UPC:: 51373438
Condition:: New
Availability:: 8-12 weeks
Weight:: 1.06 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: G647283-10mg
CAS:: 2315311-83-0
Product Size:: 10mg

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