GSK-3 and CDK inhibitor. It induces cell cycle arrest and apoptosis in leukemia cells, induces Wnt signaling to decrease egg hatching activity, and inhibits HIV-1 replication and proliferation. (C003B-255428)

Catalog No.: C003B-255428
Mfr. No.: A4577-1 mg
Mfr. Name: LKT Laboratories, Inc
Qty/UOM: 1
UOM: EA

Price: $380.31

List Price: $422.57

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Description
Specifications

Alsterpaullone exhibits anticancer, anti-angiogenic, antiviral, and neuroprotective activities. Alsterpaullone inhibits cyclin-dependent kinases (CDKs), inducing G2/M phase cell cycle arrest and apoptosis in leukemia cells. Additionally, alsterpaullone inhibits glycogen synthase kinase 3 (GSK-3), inducing Wnt signaling; in ticks, this results in anti-fertility potential, decreasing egg hatching activity. Alsterpaullone also inhibits HIV-1 replication and proliferation. In ex vivo models of Alzheimerâ€™s disease, this compound protects against neuronal death and decreases phosphorylation of tau protein.

UPC:: 51182701
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: A4577-1 mg
CAS:: 237430-03-4

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