General description
A potent and ATP-competitive inhibitor of GSK-3 (Ki = 24 nM).
An aminopyrazole compound that acts as a potent and ATP-binding site inhibitor of GSK-3 with a Ki of 24 nM.
Biochem/physiol Actions
Cell permeable: no
Primary Target
GSK-3
Product does not compete with ATP.
Reversible: no
Target Ki: 24 nM against GSK-3
Warning
Toxicity: Carcinogenic / Teratogenic (D)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Pierce, A.C., et al. 2005. J. Med. Chem.48, 1278.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51172453
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 361555-5MG
- CAS:
- 404828-08-6
