GSK-J1 lithium salt (C09-1136-053)

Aladdin

Catalog No.: C09-1136-053
Manufacturer No.: G659223-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

Price: $438.30

List Price: $487.00

GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A , with IC 50 of 60 nM towards KDM6B.Appearance:SolidIC50&: Target:IC50: 60 nM (KDM6B)In Vitro:GSK-J1 is selective for H3K27 demethylases of the KDM6

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Description
Specifications

GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A , with IC 50 of 60 nM towards KDM6B.Appearance:SolidIC50& Target:IC50: 60 nM (KDM6B)In Vitro:GSK-J1 is selective for H3K27 demethylases of the KDM6 subfamily and specifically binds to endogenous JMJD3. GSK-J1 inhibits TNF-α production by human primary macrophages in an H3K27-dependent manner. GSK-J1 inhibits the demethylase activity of KDM5CBiological Activity:GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A , with IC 50 of 60 nM towards KDM6B. Molecular Formula: C22H22LiN5O2 Molecular Weight: 395.38

UPC:: 12352107
Condition:: New
Availability:: 8-12 weeks
Weight:: 1.09 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: G659223-100mg
Product Size:: 100mg

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