General description
A partial agonist selective for α7 nAChRs (EC50 = 10 µM). Used in neuroimmunology studies, cardiovascular disease research, and Alzheimer′s disease studies.
Biochem/physiol Actions
Primary Target
α7 nAChR
Reversible: yes
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Kox, M., et al. 2011. Br. J. Anaesth.107, 559.
Kox, M., et al., 2011. Shock.36, 5.
Rosas-Ballina, M., et al. 2009. Mol. Med.15, 195.
Briggs, A., et al. 1997. Pharmacol. Biochem. Behav.57, 231.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51291906
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 5052770001