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GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE) TETRALITHIUM (C005B-091198)

Catalog No.
C005B-091198
Mfr. No.
G8634-5MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
5
UOM
MG
Price: $576.67
List Price: $640.74

Application Guanosine 5′-[γ-thio]triphosphate tetralithium salt has been used: as a component of lysis buffer in oocyte and mammalian cell patch-clamp experiments to keep the G proteins in a constantly active state to couple with G-

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Application

Guanosine 5′-[γ-thio]triphosphate tetralithium salt has been used:

  • as a component of lysis buffer
  • in oocyte and mammalian cell patch-clamp experiments to keep the G proteins in a constantly active state
  • to couple with G- protein α, to study its effect on kinase activity

Biochem/physiol Actions

GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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UPC:
51182413
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
G8634-5MG
CAS:
94825-44-2
Temperature Control Device:
Yes

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