General description
A fluorogenic, acetylated peptide substrate for HDAC′s. Based on residues 379-382 of p53, Arg-His-Lys-Lys, Ac, a site of regulatory acetylation by the p300 and CBP acetyltransferases, lysines 381, 382, 1-3, it is a suitable substrate for HDAC2, HDAC3, and HDAC6 tested so far.
Application
Study enzyme kinetics, and screen small molecule inhibitors for drug discovery and HTS applications.
Physical form
Supplied as a 5 mM solution in DMSO.
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- UPC:
- 12352209
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SRP0305-500NMOL
- Temperature Control Device:
- Yes