HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC 50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells.IC50& Target:HDAC10 58 ± 10 nM (IC 50 ) hHDAC8 920 ± 170 nM (IC 50 ) hHDAC6 2420 ± 530 nM (IC 50 )Biological Activity:HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC 50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells. Molecular Formula: C18H23N3O2 Molecular Weight: 313.39
- UPC:
- 51131743
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- H659351-10mg
- Product Size:
- 10mg
