HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.In VitroHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5); HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:HDAC8 27.2 nM (IC 50 ). Specification: 0.99 Molecular Formula: C22H19NO3 Molecular Weight: 345.39 PubChem CID: 70676597 Isomeric SMILES: COC1=CC(=C(C=C1)/C=C/C(=O)NO)C2=CC=C(C=C2)C3=CC=CC=C3
- UPC:
- 12352208
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- H647382-50mg
- CAS:
- 1417997-93-3
- Product Size:
- 50mg
