General description
Filamentous Hemagglutinin (FHA) from Bordetella pertussis is a major virulence-associated adhesion factor secreted by these bacteria. It contains an arginine-glycine-aspartate (RGD) sequence. FHA is a derivative of its precursor FhaB.
Biochem/physiol Actions
Filamentous Hemagglutinin (FHA) from Bordetella pertussis enables the attachment of bacteria to the epithelium of the upper respiratory tract. The arginine-glycine-aspartate (RGD) sequence mediates the binding of FHA to sulfated polysaccharides and pulmonary macrophage integrins.
Physical form
lyophilized from 0.05 M Tris HCL, pH 8, with 0.5 M sodium chloride and 5% sucrose
- UPC:
- 51131649
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- F5551-50UG