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hemin (c15-1218-068)

Hemin (C15-1218-068)

Catalog No.
C15-1218-068
Manufacturer No.
51280-5G
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
GR
Price: $499.59
List Price: $555.10

Application Hemin is used for the following applications: To study bacterial strains and growth conditions Used in short-term colony assays (the culture medium consists of hemin along with other components) Cell transfections It may be used in

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Application

Hemin is used for the following applications:

  • To study bacterial strains and growth conditions
  • Used in short-term colony assays (the culture medium consists of hemin along with other components)
  • Cell transfections
It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.

Biochem/physiol Actions

Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.

Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.

UPC:
51131515
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
51280-5G


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