Application
Heparan Sulfate promotes the attachment of cells in culture and induces high affinity binding of FGF-basic to cells deficient in heparin sulfate and soluble FGF receptors at a concentration of 10-100 ng/mL.
Biochem/physiol Actions
This is a multifunctional molecule. As a component of the extracellular matrix that binds to fibroblast growth factors, vascular endothelial growth factor and vascular endothelial growth factor receptors. It also acts as a docking molecule for matrilysin and other matrix metalloproteinases.
Components
Heparan sulfate proteoglycan is a large biomolecule composed of a core protein covalently bound to heparin sulfate chains that is an integral part of the basement membrane. The number of polysaccharide chains and the size of the core protein are variable according to the source.
Caution
It is recommended to store this product at 20°C, where it will retain its function for 3 years
Preparation Note
This product is isolated from the basement membrane of Engelbreth-Holm-Swarm mouse sarcoma in a solution containing 50 mM Tris HCl at pH 7.4, 150 mM NaCl, 1 mM EDTA, and 0.1 mM PMSF.
- UPC:
- 51411712
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- H4777-.1MG
