product description：Antibiotic .Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH .Anticancer compound . Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation .Antimalarial .Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor .Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols .Reduces lactate secretion and causes reductions in overall protein synthesis and production of IFN-α and TNF.application：Heptalidic acid is a sesquiterpene lactone and found to inhibit etoposide-induced apoptosis in human leukemia U937 cells. In addition, it also inhibit mammalian DNA polymerases and terminal deoxynucleotidyl transferase. Specification: ≥95% Molecular Formula: C15H20O5 Molecular Weight: 280.32 PubChem CID: 10016502 Isomeric SMILES: CC(C)C1CCC2(CO2)C3C1C=C(COC3=O)C(=O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/H275171-SCI_6222124b6e9c7c985c76b002514756b8.pdf
- UPC:
- 12352211
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- H275171-250μg
- CAS:
- 74310-84-2
- Product Size:
- 250μg
