HERBIMYCIN A FROM STREPTOMYCES HYGROSCOPICUS (C005B-058194)

Catalog No.: C005B-058194
Mfr. No.: H6649-1MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: MG

Price: $1,978.02

List Price: $2,197.80

Herbimycin A from Streptomyces hygroscopicus is a benzoquinoid ansamycin antibiotic. It is an analog of geldanamycin.

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Description
Specifications

General description

Herbimycin A from Streptomyces hygroscopicus is a benzoquinoid ansamycin antibiotic. It is an analog of geldanamycin.

Application

Herbimycin A from Streptomyces hygroscopicus has been used as an inhibitor of Src tyrosine kinase in HEK293T cells and rat intestinal epithelial cells. It has also been used to test its attenuation effect in intimal hyperplasia (IH) post balloon injury in rat carotid artery.

Biochem/physiol Actions

Herbimycin A is an inducer of heat shock protein (HSP). It increases HSP expression resulting in the attenuation of ischemia reperfusion induced pulmonary injury.

An antibiotic that inhibits protein tyrosine kinase. Herbimycin A is a potent inhibitor of angiogenesis.

Caution

Hygroscopic and photosensitive

UPC:: 51111733
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: H6649-1MG
CAS:: 70563-58-5

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