The flavones and flavonoids are a widespread group of natural products with a variety of reported beneficial health effects. Flavonoids have been implicated as possible active agents in the dietary benefits of citrus fruits. Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in Hep-G2 cells and reduces ApoB protein synthesis in a dose-dependent manner. The EC50 for these responses is approximately 50 µM.{10842} Hesperetin also inhibits histamine release from IgE-challenged RBL-2H3 cells, with a potency comparable to the commercial anti-allergy drug azelastine.{12523}
- UPC:
- 12350000
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 10006084-100000
- CAS:
- 520-33-2
